Description

2-(2,2-Difluoro-Propylamino)-Ethanol is a specialized organofluorine compound featuring both amino and hydroxyl functional groups, making it a valuable intermediate for advanced chemical synthesis. This compound is particularly significant for its role in introducing fluorine-containing motifs into target molecules, which can dramatically alter their physical, chemical, and biological properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to leverage fluorine chemistry for product innovation.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluoroalkylaminoethanol moiety enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Surface Modification Agent: Imparts unique surface properties in specialty coatings and polymers, improving hydrophobicity and chemical resistance.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring structure-activity relationships (SAR) in medicinal chemistry.
• Fluorinated Surfactant Precursor: Used in the manufacture of high-performance fluorosurfactants for demanding industrial applications.

Basic Information

Product Name	2-(2,2-Difluoro-Propylamino)-Ethanol
CAS No.	406-99-5
Molecular Formula	C5H11F2NO
Molecular Weight	139.14 g/mol
Synonyms	2-[(2,2-Difluoropropyl)amino]ethanol; N-(2,2-Difluoropropyl)ethanolamine; Ethanol, 2-[(2,2-difluoropropyl)amino]-; 2-(2,2-Difluoropropylamino)ethanol; 2-Aminoethanol, N-(2,2-difluoropropyl)-; 406-99-5; 2-(2,2-Difluoropropan-1-ylamino)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 2-(2,2-Difluoro-Propylamino)-Ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets precise customer specifications and internal standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. Due to its chemical nature, it should be handled and stored with appropriate precautions for fluorides/strong alkali compounds.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.