Description

2-Bromo-4,4,4-Trifluorobutane is a versatile fluorinated organic bromide building block, valued for its unique combination of a reactive bromine handle and a trifluoromethyl group. This compound is essential for introducing the trifluoroethyl moiety into complex molecules, a key modification for enhancing metabolic stability, lipophilicity, and bioavailability. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in synthesis and R&D.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoroethyl group to modulate pharmacokinetic properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to incorporate the -CH2CF3 moiety into target molecules in medicinal and material chemistry.
• Fluorinated Surfactant & Polymer Modification: Used to introduce fluorine into polymers and surfactants, altering surface properties like oil and water repellency.

Basic Information

Product Name	2-Bromo-4,4,4-Trifluorobutane
CAS No.	406-47-3
Molecular Formula	C4H6BrF3
Molecular Weight	191.00 g/mol
Synonyms	4,4,4-Trifluoro-2-bromobutane; 2-Bromo-4,4,4-trifluorobutane; 1-Bromo-3-trifluoromethylpropane; Butane, 2-bromo-4,4,4-trifluoro-; 3-(Trifluoromethyl)propyl bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,4,4-Trifluorobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.