Description

4,4,4-Trifluorobuta-1,2-Diene (CAS NO 406-40-6) is a highly versatile fluorinated diene building block, prized for its unique reactivity profile in advanced chemical synthesis. Its core value lies in enabling the efficient introduction of the trifluoromethyl group, a key moiety for modulating the physical, chemical, and biological properties of target molecules. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with enhanced stability, bioavailability, or specific performance characteristics.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring the trifluoromethyl group for metabolic stability and improved pharmacokinetics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Fluorinated Polymer & Material Science: Serves as a monomer or co-monomer for creating specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Synthesis & Catalysis: Acts as a key reagent in Diels-Alder reactions and other cycloadditions for constructing complex, fluorinated cyclic frameworks in fine chemical production.
• Liquid Crystal & Electronic Material Precursor: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.

Basic Information

Product Name	4,4,4-Trifluorobuta-1,2-Diene
CAS No.	406-40-6
Molecular Formula	C4H3F3
Molecular Weight	108.06 g/mol
Synonyms	1,1,1-Trifluorobuta-1,3-diene; 3,3,3-Trifluoro-1,2-butadiene; 3,3,3-Trifluoro-1,2-propadiene; 4,4,4-Trifluoro-1,2-butadiene; Trifluorobuta-1,2-diene; 1,2-Butadiene, 4,4,4-trifluoro-; 3,3,3-Trifluoroallene
EINECS	Contact for details

Quality Control

Every batch of 4,4,4-Trifluorobuta-1,2-Diene is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including GC and NMR analysis, to ensure compliance with agreed specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are a standard part of our commitment to supply chain transparency.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated area, preferably at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Containers should be kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.