Description

1,1,1-Trifluoro-2,3-Epoxybutane is a versatile fluorinated epoxide building block, offering a unique combination of reactivity and fluorine-derived properties. Its value lies in enabling the synthesis of complex molecules with enhanced stability, lipophilicity, and metabolic resistance. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate trifluoromethyl groups into their products. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethyl group into active pharmaceutical ingredients (APIs), potentially improving drug bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance biological activity and environmental persistence.
• Specialty Polymer & Resin Modifier: Serves as a monomer or cross-linking agent for creating fluorinated polymers with superior chemical resistance, low surface energy, and thermal stability.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and dielectric materials.
• Organic Synthesis Building Block: Utilized in ring-opening reactions, nucleophilic additions, and as a precursor for various fluorinated alcohols, amines, and other derivatives in fine chemical production.

Basic Information

Product Name	1,1,1-Trifluoro-2,3-Epoxybutane
CAS No.	406-30-4
Molecular Formula	C₄H₅F₃O
Molecular Weight	126.08 g/mol
Synonyms	3,3,3-Trifluoro-1,2-epoxybutane; 1,1,1-Trifluoro-2,3-butylene oxide; 2-(Trifluoromethyl)oxirane; 3,3,3-Trifluoro-1,2-epoxybutane; 1,2-Epoxy-3,3,3-trifluorobutane; 3,3,3-Trifluoro-1,2-butylene oxide; TFEB
EINECS	206-981-5

Quality Control

Our 1,1,1-Trifluoro-2,3-Epoxybutane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and moisture analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee reliable performance in your sensitive synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.