Description

(4-Fluoro-Benzyl)-Methyl-Amine is a versatile fluorinated aromatic amine building block of significant importance in modern synthetic chemistry. Its value lies in its bifunctional structure, featuring both a reactive primary amine and a fluorinated benzyl group, enabling its use in the synthesis of complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags, affinity probes, and other tools for studying biological systems and drug-target interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(4-Fluoro-Benzyl)-Methyl-Amine
CAS No.	405-66-3
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	1-(4-Fluorophenyl)-N-methylmethanamine; N-Methyl-1-(4-fluorophenyl)methanamine; N-Methyl-4-fluorobenzylamine; 4-Fluoro-N-methylbenzylamine; p-Fluorobenzylmethylamine; N-Methyl-(4-fluorobenzyl)amine; (4-Fluorophenyl)-N-methylmethanamine; α-(Methylamino)-4-fluorotoluene
EINECS	Contact for details

Quality Control

Our (4-Fluoro-Benzyl)-Methyl-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.