Description

4-Fluorophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the acetic acid side chain, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs) containing a fluorophenyl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Peptide Mimetics & Bio-conjugation: The carboxylic acid group allows for coupling reactions to create peptide analogs or for labeling biomolecules.
• Fine Chemical & Catalyst Ligand Synthesis: Employed in the preparation of specialized ligands for asymmetric catalysis and other high-value fine chemicals.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine-containing aromatic groups into polymer chains, altering material properties.

Basic Information

Product Name	4-Fluorophenylacetic Acid
CAS No.	405-50-5
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	(4-Fluorophenyl)acetic Acid; p-Fluorophenylacetic Acid; 2-(4-Fluorophenyl)acetic Acid; 4-Fluoro-α-toluic Acid; 4-Fluorobenzeneacetic Acid; NSC 404087; FPA; p-Fluorobenzylcarboxylic Acid
EINECS	206-974-8

Quality Control

Our 4-Fluorophenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	83 - 87 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.