Description

1-Fluoro-4-(2-Phenylethynyl)Benzene is a high-purity organic building block featuring a fluorinated aromatic core linked to a phenylacetylene moiety. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, especially those requiring fluorinated aromatic structures for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the fluorine atom and acetylene linker contribute to biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor in the creation of advanced polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Cross-Coupling Reactions: An excellent substrate for Sonogashira, Heck, and Suzuki-Miyaura couplings to construct complex conjugated systems for various applications.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	1-Fluoro-4-(2-Phenylethynyl)Benzene
CAS No.	405-29-8
Molecular Formula	C14H9F
Molecular Weight	196.22 g/mol
Synonyms	4-Fluoro-4'-ethynyl-1,1'-biphenyl; 4-Ethynyl-4'-fluorobiphenyl; 1-Fluoro-4-(phenylethynyl)benzene; p-Fluorophenyl phenylacetylene; 4-Fluorophenyl phenylacetylene; (4-Fluorophenyl)(phenyl)acetylene; 405-29-8; 1-Fluoro-4-(2-phenylethynyl)benzene
EINECS	Contact for details

Quality Control

Every batch of 1-Fluoro-4-(2-Phenylethynyl)Benzene is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.