Description

3-Fluoro-4-Methoxyphenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both electron-donating methoxy and electron-withdrawing nitrile groups adjacent to a fluorine atom, makes it a critical intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including kinase inhibitors, CNS-active compounds, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving electronic properties and device performance.
• Functional Polymer Monomer: Employed in the creation of specialty polymers with tailored properties such as chemical resistance, thermal stability, and specific optical characteristics.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring novel fluorination chemistry and developing new synthetic methodologies.
• Fine Chemical Production: Acts as a precursor for other fine chemicals and fluorinated aromatic compounds used in various high-value industrial applications.

Basic Information

Item	Detail
Product Name	3-Fluoro-4-Methoxyphenylacetonitrile
CAS No.	404-90-0
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	2-(3-Fluoro-4-methoxyphenyl)acetonitrile; (3-Fluoro-4-methoxyphenyl)acetonitrile; 3-Fluoro-4-methoxybenzyl cyanide; 3-Fluoro-p-anisylacetonitrile; 4-Methoxy-3-fluorophenylacetonitrile; 404-90-0; 3-Fluoro-4-methoxybenzeneacetonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxyphenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.