Description

N,N''-Bis-(3-Trifluoromethyl-Phenyl)-Malonamide is a specialized organic compound featuring a malonamide core flanked by two trifluoromethylphenyl groups, imparting unique electronic and steric properties. This structure makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex molecules with enhanced stability and specific functionality. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or requiring metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl groups can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, or organic electronic materials due to its rigid aromatic structure.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Advanced Organic Synthesis: Acts as a precursor for heterocyclic compounds or as a ligand in catalytic systems, leveraging its electron-withdrawing characteristics.

Basic Information

Product Name	N,N''-Bis-(3-Trifluoromethyl-Phenyl)-Malonamide
CAS No.	402-21-1
Molecular Formula	C₁₇H₁₂F₆N₂O₂
Molecular Weight	390.28 g/mol
Synonyms	N,N'-Bis[3-(trifluoromethyl)phenyl]propanediamide; 1,3-Bis(3-trifluoromethylphenyl)malonamide; Malonamide, N,N'-bis[3-(trifluoromethyl)phenyl]-; Propanediamide, N,N'-bis[3-(trifluoromethyl)phenyl]-; 3,3'-(1,3-Dioxo-1,3-propanediyl)bis[α,α,α-trifluorotoluene]; Bis(3-trifluoromethylphenyl)malonamide
EINECS	Contact for details

Quality Control

Our N,N''-Bis-(3-Trifluoromethyl-Phenyl)-Malonamide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting R&D and production standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.