Description

n-Butyltrifluoroacetamide is a specialized fluorinated amide compound with the CAS registry number 400-59-9. This chemical is valued for its role as a versatile building block and reagent in advanced organic synthesis, particularly in the introduction of the trifluoroacetyl group. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the preparation of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroacetamide group can contribute to biological activity.
• Organic Synthesis Reagent: Acts as a trifluoroacetylating agent in peptide chemistry and for protecting amine groups during multi-step synthetic sequences.
• Material Science Research: Employed in the development of specialty polymers, coatings, and liquid crystals that benefit from fluorine's unique properties.
• Chemical Reference Standard: Utilized as a high-purity analytical standard in quality control and method development for chromatographic analysis.

Basic Information

Product Name	n-Butyltrifluoroacetamide
CAS No.	400-59-9
Molecular Formula	C6H10F3NO
Molecular Weight	169.15 g/mol
Synonyms	N-Butyltrifluoroacetamide; Butyltrifluoroacetamide; Trifluoro-N-butylacetamide; N-Butyl-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-butylacetamide; Butylamide, N-(trifluoroacetyl)-; TFAA-Bu; TFA-n-BuNH2
EINECS	206-924-4

Quality Control

Our n-Butyltrifluoroacetamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.