Description

Trifluoroacetic Acid 1-Methylethenyl Ester is a specialized fluorinated organic compound, also known as Trifluoroacetic Acid Isopropenyl Ester. This high-purity reagent is valued for its role as a versatile building block in advanced organic synthesis, particularly for introducing the trifluoroacetyl group. It is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoroacetyl protecting groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances biological activity.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the development of specialty polymers and coatings with unique chemical resistance.
• Organic Synthesis Reagent: Employed in laboratories for acylations and as a precursor to other trifluoromethyl-containing compounds.
• Fluorine Chemistry Research: A valuable tool in academic and industrial R&D for exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	Trifluoroacetic Acid 1-Methylethenyl Ester
CAS No.	400-39-5
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	Isopropenyl Trifluoroacetate; 2-Propenyl Trifluoroacetate; Trifluoroacetic Acid Isopropenyl Ester; 1-Methylethenyl Trifluoroacetate; 2-Methyl-1-propenyl Trifluoroacetate; TFA Isopropenyl Ester; CF3COOCH=C(CH3)2
EINECS	206-915-0

Quality Control

Our Trifluoroacetic Acid 1-Methylethenyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting traceability and compliance for cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed and handle in a fume hood. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.20 g/mL
Boiling Point	~85-90°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.