Description

1,4-Dichloro-2,5-Difluorobenzene is a high-purity, multi-halogenated benzene derivative serving as a critical building block in advanced chemical synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop new active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene core.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides, where the halogen atoms facilitate further functionalization.
• Liquid Crystal Materials: Serves as a building block for fluorine-containing liquid crystal compounds used in display technologies.
• Polymer & Material Science: Employed in the production of specialty polymers, including high-performance engineering plastics and resins.
• Organic Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce aromatic halogen functionalities.
• Chemical Research & Development: Utilized in R&D laboratories for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	1,4-Dichloro-2,5-Difluorobenzene
CAS No.	400-05-5
Molecular Formula	C6H2Cl2F2
Molecular Weight	182.98 g/mol
Synonyms	2,5-Difluoro-1,4-dichlorobenzene; 1,4-Dichloro-2,5-difluorobenzene; Benzene, 1,4-dichloro-2,5-difluoro-; p-Dichloro-o,p-difluorobenzene; NSC 403058; 400-05-5; 2,5-Difluoro-p-dichlorobenzene
EINECS	Contact for details

Quality Control

Our 1,4-Dichloro-2,5-Difluorobenzene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥98.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.