Description

Ethyl 2-Ethyl-2-Isoamylcyanoacetate is a specialized cyanoacetate ester derivative, serving as a versatile and high-value chemical intermediate in advanced organic synthesis. Its unique branched alkyl structure makes it particularly valuable for constructing complex molecular frameworks where steric control and specific lipophilicity are required. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical sectors, enabling the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with complex ester and nitrile functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structure contributes to specific biological activity and environmental stability.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers requiring tailored solubility and reactivity profiles.
• Organic Synthesis Reagent: Employed in Knoevenagel condensations and other C-C bond-forming reactions to introduce the cyanoacetate moiety into target molecules.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing esters with specific fruity or floral notes, though typically in high-purity grades.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymeric materials with specific functional groups.

Basic Information

Product Name	Ethyl 2-Ethyl-2-Isoamylcyanoacetate
CAS No.	399556-78-6
Molecular Formula	C₁₂H₂₁NO₂
Molecular Weight	211.30 g/mol
Synonyms	Ethyl 2-Cyano-2-ethyl-4-methylpentanoate; 2-Ethyl-2-isoamylcyanoacetic Acid Ethyl Ester; Ethyl α-Cyano-α-ethylcaproate; Ethyl 2-Ethyl-2-(3-methylbutyl)cyanoacetate; Cyanoacetic Acid, 2-Ethyl-2-isoamyl-, Ethyl Ester; NSC 405124; 399556-78-6
EINECS	Contact for details

Quality Control

Our Ethyl 2-Ethyl-2-Isoamylcyanoacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We can support production under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.