Description

(Hyp474,477,Gln479)-Cyclo-α-Fetoglobulin (471-479) (Human, Lowland Gorilla) is a synthetic, cyclic peptide fragment derived from the α-fetoglobulin protein sequence, engineered to incorporate specific hydroxyproline and glutamine modifications. This specialized peptide is critical for advanced biochemical research and development, offering a high-purity reference standard for structural and functional studies. It is primarily utilized by pharmaceutical R&D teams, diagnostic developers, and academic researchers focused on oncology, immunology, and comparative primatology.

Application

• Biochemical Research Standard: Serves as a high-purity reference material for mass spectrometry, chromatography, and protein characterization studies.
• Immunological Assay Development: Used in the development and calibration of immunoassays (ELISA, Western Blot) targeting α-fetoglobulin epitopes.
• Oncology Research: Employed as a tool peptide in cancer biomarker research to study the role and modulation of α-fetoglobulin-related pathways.
• Comparative Biomedical Studies: Facilitates research into protein evolution and functional differences between human and non-human primate (Lowland Gorilla) biological systems.
• Pharmaceutical Development: Acts as a key intermediate or reference compound in the discovery and validation stages of novel therapeutic candidates.
• Antigen Production: Can be used for the generation of specific antibodies for diagnostic or research purposes.

Basic Information

Product Name	(Hyp474,477,Gln479)-Cyclo-α-Fetoglobulin (471-479) (Human, Lowland Gorilla)
CAS No.	393827-70-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclo(471-479)-α-Fetoglobulin (Human, Gorilla); Cyclic AFP (471-479) peptide; Modified α-Fetoprotein Fragment 471-479; Cyclo-AFP(471-479) with Hyp and Gln substitutions; Synthetic cyclic peptide CAS 393827-70-8; α-1-Fetoprotein cyclic fragment; Research peptide 393827-70-8
EINECS	Contact for details

Quality Control

Our (Hyp474,477,Gln479)-Cyclo-α-Fetoglobulin (471-479) (Human, Lowland Gorilla) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.