Description

3-Chloro-n-(2,4-Difluorophenyl)Propanamide is a specialized organic intermediate featuring a chloroalkyl chain and a difluorinated aromatic ring, offering unique reactivity for advanced synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel material science applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-infective properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Chemical Research & Development: Acts as a versatile scaffold for medicinal chemistry and process chemistry, enabling the exploration of new chemical spaces and structure-activity relationships (SAR).
• Material Science: Potential building block for the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its halogenated aromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	3-Chloro-n-(2,4-Difluorophenyl)Propanamide
CAS No.	392741-26-3
Molecular Formula	C9H8ClF2NO
Molecular Weight	219.62 g/mol
Synonyms	3-Chloro-N-(2,4-difluorophenyl)propanamide; N-(2,4-Difluorophenyl)-3-chloropropanamide; 3-Chloropropanamide, N-(2,4-difluorophenyl)-; Propanamide, 3-chloro-N-(2,4-difluorophenyl)-; 392741-26-3; 2,4-Difluoro-3-chloropropionanilide
EINECS	Contact for details

Quality Control

Our 3-Chloro-n-(2,4-Difluorophenyl)Propanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. For advanced applications, we can supply material that meets research-grade or custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.