Description

5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, 2-Benzoylhydrazide is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines a thienopyridine core with a trifluoromethyl group and a benzoylhydrazide moiety, offering significant potential for modulating biological activity and physicochemical properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by fine chemical manufacturers producing specialized intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of new drug candidates, particularly for targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance bioavailability and metabolic stability.
• Material Science Precursor: Acts as a specialized monomer or additive in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its distinctive heterocyclic scaffold.
• Fine Chemical Synthesis: Employed as a key intermediate for constructing complex molecules in custom synthesis and contract manufacturing projects.

Basic Information

Product Name	5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, 2-Benzoylhydrazide
CAS No.	390357-09-2
Molecular Formula	C₁₆H₁₀F₃N₃O₂S
Molecular Weight	365.33 g/mol
Synonyms	2-Benzoylhydrazide of 5-(Trifluoromethyl)thieno[3,2-b]pyridine-6-carboxylic acid; 5-(Trifluoromethyl)thieno[3,2-b]pyridine-6-carboxylic acid benzoylhydrazide; 390357-09-2; 5-Trifluoromethylthieno[3,2-b]pyridine-6-carboxylic acid 2-benzoylhydrazide; Thieno[3,2-b]pyridine-6-carboxylic acid, 5-(trifluoromethyl)-, 2-benzoylhydrazide
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)Thieno[3,2-B]Pyridine-6-Carboxylic Acid, 2-Benzoylhydrazide adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical specifications. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.