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(R)-1-[(R)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl]Ethyldiphenylphosphine CAS NO 388079-58-1
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CAS No.:388079-58-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-1-[(R)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl]Ethyldiphenylphosphine is a highly specialized chiral ferrocenyl diphosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, which are essential for the efficient and sustainable synthesis of single-enantiomer compounds. This ligand is primarily needed by research institutions and pharmaceutical/agrochemical companies developing advanced chiral intermediates, active pharmaceutical ingredients (APIs), and fine chemicals.
Application
- As a chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure amino acids, amines, and alcohols.
- Catalyst component in asymmetric C-C bond-forming reactions, such as cross-couplings and allylic substitutions.
- Key reagent in academic and industrial R&D for developing novel catalytic processes in organic synthesis.
- Used in the synthesis of chiral pharmaceutical intermediates and active ingredients requiring high optical purity.
- Application in the preparation of specialty fine chemicals and advanced materials where stereochemical control is paramount.
- Potential use in homogeneous catalysis research for exploring new reaction mechanisms and selectivities.
Basic Information
| Product Name | (R)-1-[(R)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl]Ethyldiphenylphosphine |
| CAS No. | 388079-58-1 |
| Molecular Formula | C46H38FeP2 |
| Molecular Weight | 708.57 g/mol |
| Synonyms | (R,R)-JOSIPHOS; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(2-methoxyphenyl)phosphine (common misassignment); (R)-1-[(R)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldiphenylphosphine; Josiphos ligand SL-J009-1; Ferrocenyl diphosphine ligand; Chiral ferrocene-based ligand; (R,R)-1-[(R)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldiphenylphosphine |
| EINECS | Contact for details |
Quality Control
Our (R)-1-[(R)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl]Ethyldiphenylphosphine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identity. We support compliance with cGMP and ISO standards for advanced chemical manufacturing.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and catalytic activity.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red powder or crystals |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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