Description

1-Acetyl-n-Cyclopropylpiperidin-4-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core and cyclopropyl substituent. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutic research. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Biochemical Tool Compound: Employed in pharmacological assays and as a reference standard in analytical method development.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and drug discovery programs.

Basic Information

Product Name	1-Acetyl-n-Cyclopropylpiperidin-4-Amine
CAS No.	387358-46-5
Molecular Formula	C10H18N2O
Molecular Weight	182.26 g/mol
Synonyms	N-(4-Aminopiperidin-1-yl)-1-cyclopropylethanone; 1-Cyclopropylethanone N-(4-aminopiperidin-1-yl); 4-Amino-1-(1-cyclopropanecarbonyl)piperidine; 1-Acetyl-4-aminopiperidine, N-cyclopropyl derivative; 1-(1-Cyclopropylethylideneamino)piperidin-4-amine; 4-Amino-1-(cyclopropylcarbonyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Acetyl-n-Cyclopropylpiperidin-4-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and spectroscopic confirmation (NMR, IR, MS). Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.