Description

6-(Triethylammonium)Hexyl Methanethiosulfonate Bromide is a specialized organosulfur compound with a reactive methanethiosulfonate (MTS) group, widely used as a key reagent in bioconjugation and protein chemistry. Its primary value lies in its ability to selectively modify cysteine residues, enabling the site-specific labeling, crosslinking, or functionalization of biomolecules. This makes it an essential tool for researchers and manufacturers in the fields of biopharmaceutical development, proteomics, diagnostic assay production, and advanced materials science.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, antibodies, and peptides with fluorophores, biotin, or other functional moieties via cysteine residues.
• Protein Crosslinking: Used in structural biology and drug discovery to study protein-protein interactions or create stable protein complexes.
• Surface Functionalization: Modification of gold nanoparticles, biosensor chips, or other surfaces to create bioactive interfaces for diagnostics.
• Affinity Chromatography Ligand Synthesis: Immobilization of small molecules or peptides onto solid supports for purification processes.
• Proteomics Research: As a tool for studying protein structure, function, and dynamics through selective chemical modification.
• Antibody-Drug Conjugate (ADC) Development: A potential building block in the synthesis of linkers for targeted cancer therapies.
• Polymer Science: Incorporation into polymer backbones or as a chain-transfer agent to introduce specific functional groups.

Basic Information

Product Name	6-(Triethylammonium)Hexyl Methanethiosulfonate Bromide
CAS No.	386229-78-3
Molecular Formula	C14H32BrNO2S2
Molecular Weight	390.44 g/mol
Synonyms	6-(Triethylammonio)hexyl methanethiosulfonate bromide; MTS-hexyl-TEA bromide; Hexyl MTS reagent; (6-Methanethiosulfonatohexyl)triethylammonium bromide; Thiol-reactive crosslinker; MTSEA hexyl derivative; Protein labeling reagent; Cysteine-specific modifier
EINECS	Contact for details

Quality Control

Our production of 6-(Triethylammonium)Hexyl Methanethiosulfonate Bromide adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by multiple analytical techniques, including NMR, HPLC, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.