Description

Benzonitrile, 2-Amino-5-Methoxy-4-[3-(4-Morpholinyl)Propoxy]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular structure incorporating both morpholine and benzonitrile moieties. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates with targeted biological activity.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Research & Development: Essential for medicinal chemistry research, enabling the exploration of new chemical entities and structure-activity relationships.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for creating complex molecules with specific functional groups.
• Preclinical Drug Development: Serves as a critical material in the production of compounds for pharmacological and toxicological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of drug substances.

Basic Information

Product Name	Benzonitrile, 2-Amino-5-Methoxy-4-[3-(4-Morpholinyl)Propoxy]-
CAS No.	385784-72-5
Molecular Formula	C15H21N3O2
Molecular Weight	275.35 g/mol
Synonyms	2-Amino-5-methoxy-4-[3-(4-morpholinyl)propoxy]benzonitrile; 4-(3-Morpholinopropoxy)-2-amino-5-methoxybenzonitrile; 2-Amino-4-(3-morpholin-4-ylpropoxy)-5-methoxybenzonitrile; 385784-72-5; 2-Amino-5-methoxy-4-(3-morpholinopropoxy)benzonitrile; Benzonitrile, 2-amino-5-methoxy-4-[3-(4-morpholinyl)propoxy]-; 4-(3-Morpholinopropoxy)-5-methoxy-2-aminobenzonitrile
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-Amino-5-Methoxy-4-[3-(4-Morpholinyl)Propoxy]- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.