Description

1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine-n-Diethylenetriaminepentaacetic Acid (Ammonium Salt) is a high-purity, synthetic phospholipid derivative conjugated with a powerful metal chelator, DTPA. This compound is engineered for advanced applications requiring precise lipid-based encapsulation and targeted metal ion binding. It is a critical material for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of next-generation diagnostic agents and targeted therapeutic delivery systems.

Application

• Liposomal Formulation: A key functional lipid for constructing liposomes with surface-chelating properties, used in drug delivery and diagnostic imaging.
• Contrast Agent Development: Serves as a bifunctional chelator for gadolinium (Gd³⁺) or other lanthanides in the creation of targeted MRI contrast agents.
• Radiolabeling Platforms: Used to prepare phospholipid conjugates for radiolabeling with isotopes like Indium-111 (¹¹¹In) or Technetium-99m (⁹⁹ᵐTc) for SPECT imaging.
• Targeted Therapy: Enables the surface functionalization of nanocarriers for active targeting, enhancing site-specific delivery of chemotherapeutic agents.
• Research Reagent: Employed in biochemical and biophysical research to study membrane dynamics, metal-lipid interactions, and cell signaling pathways.
• Diagnostic Kits: A component in the development of in-vitro diagnostic kits and assays that require metal ion sequestration or signal amplification.

Basic Information

Item	Details
Product Name	1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine-n-Diethylenetriaminepentaacetic Acid (Ammonium Salt)
CAS No.	384832-89-7
Molecular Formula	C₄₉H₉₈N₆O₁₇P • xNH₃
Molecular Weight	~1125.3 g/mol (free acid, approximate)
Synonyms	DMPE-DTPA (Ammonium Salt); 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid ammonium salt; DTPA-DMPE; 14:0 PE-DTPA; Phospholipid-DTPA conjugate; DMPE-DTPA-NH₄; DTPA-PE (C14:0); DTPA-dimyristoylphosphatidylethanolamine
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine-n-Diethylenetriaminepentaacetic Acid (Ammonium Salt) is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Phosphorus Content)	≥ 85% (of theoretical)
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.