Description

tert-Butyl 2-Bromo-4-Chlorophenylcarbamate is a high-purity, protected aniline derivative serving as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a versatile, reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for heterocyclic and functionalized aromatic systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing halogenated aromatic or heterocyclic moieties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the 2-bromo-4-chloro substitution pattern is pharmacologically relevant.
• Material Science Research: Serves as a monomer or precursor for functionalized polymers and advanced organic materials with specific electronic or optical properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex organic molecules for clients.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical transformations involving protected anilines.

Basic Information

Product Name	tert-Butyl 2-Bromo-4-Chlorophenylcarbamate
CAS No.	384793-16-2
Molecular Formula	C11H13BrClNO2
Molecular Weight	306.58 g/mol
Synonyms	Carbamic acid, N-(2-bromo-4-chlorophenyl)-, 1,1-dimethylethyl ester; 2-Bromo-4-chlorophenylcarbamic acid tert-butyl ester; tert-Butyl N-(2-bromo-4-chlorophenyl)carbamate; BOC-2-Bromo-4-chloroaniline; N-Boc-2-bromo-4-chloroaniline; N-(tert-Butoxycarbonyl)-2-bromo-4-chloroaniline; 1,1-Dimethylethyl (2-bromo-4-chlorophenyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-4-Chlorophenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP (current Good Manufacturing Practice) for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.