Description

Ba-Alanine, n-[1-(2,5-Dioxocyclopentylidene)Ethyl]- (9Ci) is a specialized chemical intermediate featuring a reactive maleimide moiety linked to an alanine derivative. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and specialty chemical industries for applications such as bioconjugation and polymer modification.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring targeted delivery systems.
• Bioconjugation Reagent: Utilized for coupling peptides, proteins, or antibodies to other molecules, polymers, or surfaces via its reactive maleimide group, which selectively binds to thiols.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the production of specialty polymers with tailored properties for medical or industrial use.
• Proteomics Research: Employed in the design and synthesis of probes and affinity tags for studying protein structure, function, and interactions.
• Material Science: Used in the development of advanced functional materials, including hydrogels and smart coatings, where precise chemical linkage is required.
• Chemical Biology Tool: Facilitates the creation of chemical probes for labeling and visualizing biological processes within cells.

Basic Information

Product Name	Ba-Alanine, n-[1-(2,5-Dioxocyclopentylidene)Ethyl]- (9Ci)
CAS No.	383411-36-7
Molecular Formula	C10H11NO4
Molecular Weight	209.20 g/mol
Synonyms	N-[1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]-β-alanine; 3-[1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethylamino]propanoic acid; Maleimide alanine derivative; 1-[1-(2-Carboxyethylamino)ethyl]-1H-pyrrole-2,5-dione; β-Alanine, N-[1-(2,5-dioxo-1-cyclopenten-1-yl)ethyl]- (9CI); N-(1-Maleimidoethyl)-β-alanine
EINECS	Contact for details

Quality Control

Our Ba-Alanine, n-[1-(2,5-Dioxocyclopentylidene)Ethyl]- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We can support development projects with custom purity grades, including research and cGMP standards for preclinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.