Description

3-(4-Fluoroanilino)-1-(2-thienyl)-1-propanone is a specialized organic building block featuring a unique molecular scaffold combining fluoroaniline and thiophene motifs. This compound matters as a key intermediate in the research and development of novel pharmaceuticals and advanced materials, where its structure enables fine-tuning of electronic and binding properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing target molecules with potential biological activity or specific functional characteristics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging the bioactivity of the fluoroaniline and thiophene groups.
• Material Science: Acts as a monomer or building block for constructing organic semiconductors, conductive polymers, or nonlinear optical (NLO) materials.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function or protein-ligand interactions in biochemical assays.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(4-Fluoroanilino)-1-(2-thienyl)-1-propanone
CAS No.	383389-77-3
Molecular Formula	C₁₃H₁₂FNOS
Molecular Weight	249.31 g/mol
Synonyms	1-(2-Thienyl)-3-[(4-fluorophenyl)amino]-1-propanone; 3-[(4-Fluorophenyl)amino]-1-(2-thienyl)-1-propanone; N-(4-Fluorophenyl)-3-oxo-3-(2-thienyl)propan-1-amine; 3-(4-Fluoroanilino)-1-(thiophen-2-yl)propan-1-one; 383389-77-3; Propanone, 3-[(4-fluorophenyl)amino]-1-(2-thienyl)-
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoroanilino)-1-(2-thienyl)-1-propanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.