Description

2-[3-(Trifluoromethyl)Phenyl]Piperidine is a high-value, fluorinated piperidine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique combination of the piperidine scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical and pharmacological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) targets, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers or organic electronic materials that require fluorinated aromatic components.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Phenyl]Piperidine
CAS No.	383128-75-4
Molecular Formula	C12H14F3N
Molecular Weight	229.24 g/mol
Synonyms	2-(3-(Trifluoromethyl)phenyl)piperidine; 3-(Trifluoromethyl)-2-piperidinylbenzene; 2-(α,α,α-Trifluoro-m-tolyl)piperidine; 1-(3-(Trifluoromethyl)phenyl)-2-piperidine; Piperidine, 2-[3-(trifluoromethyl)phenyl]-; m-Trifluoromethyl-2-piperidinylbenzene
EINECS	Contact for details

Quality Control

Our 2-[3-(Trifluoromethyl)Phenyl]Piperidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with various standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.