Description

2-Pyrrolidinecarboxamide,1-Ethyl-,(2R)-(9Ci) is a chiral, non-natural proline derivative of significant interest in advanced organic synthesis. This compound matters as a versatile building block for constructing complex molecules with precise stereochemistry, which is critical for developing bioactive compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.
• Asymmetric Catalyst Ligand: Used in the design and synthesis of novel organocatalysts or metal-complex ligands for enantioselective transformations.
• Peptidomimetics & Bioactive Molecule Synthesis: Acts as a constrained proline analog for creating peptide-like structures with enhanced metabolic stability and target selectivity.
• Agrochemical Research: Employed in the synthesis of chiral herbicides, fungicides, or plant growth regulators.
• Academic & R&D Laboratories: Utilized in fundamental research exploring new synthetic methodologies and structure-activity relationships.
• Custom Synthesis & Contract Manufacturing: A starting material for the bespoke production of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	2-Pyrrolidinecarboxamide,1-Ethyl-,(2R)-(9Ci)
CAS No.	381670-32-2
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(R)-1-Ethylpyrrolidine-2-carboxamide; (2R)-1-Ethyl-2-pyrrolidinecarboxamide; (R)-1-Ethyl-2-carbamoylpyrrolidine; 1-Ethyl-D-prolinamide; (R)-N-Ethylprolinamide; (R)-1-Ethylproline amide; (R)-1-Ethyl-2-pyrrolidine carboxylic acid amide; (R)-1-Ethylpyrrolidine-2-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a focus on high chiral purity and chemical integrity, supported by comprehensive analytical characterization. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.