Description

Pertuzumab CAS NO 380610-27-5 is a recombinant humanized monoclonal antibody designed for targeted cancer therapy. It plays a critical role in oncology by specifically inhibiting the dimerization of the HER2 receptor, a key driver in certain aggressive breast cancers. This product is essential for pharmaceutical manufacturers, clinical research organizations, and biotechnology companies engaged in the development and production of advanced biotherapeutic agents for HER2-positive metastatic breast cancer.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of targeted cancer therapeutics.
• Key component in biosimilar development and manufacturing for HER2-targeted therapies.
• Critical reagent in preclinical and clinical research studies investigating HER2 signaling pathways.
• Reference standard for quality control and analytical method development in biopharmaceutical labs.
• Used in combination therapy regimens with other chemotherapeutic agents for enhanced efficacy.

Basic Information

Item	Detail
Product Name	Pertuzumab
CAS No.	380610-27-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pertuzumab; rhuMAb 2C4; Omnitarg; Anti-HER2 Monoclonal Antibody; Recombinant Humanized Anti-HER2 Antibody; 2C4 Antibody; HER Dimerization Inhibitor; Perjeta (Brand Name)
EINECS	Contact for details

Quality Control

Our Pertuzumab is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, aligning with ICH Q6B guidelines for biotechnological products. Certificates of Analysis (COA) documenting critical quality attributes such as purity by SEC-HPLC, host cell protein levels, and biological activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Do not freeze. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear to slightly opalescent solution
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 98.0% (Monomer)
Protein Content (UV-A280)	As per COA
Potency (Cell-based assay)	As per COA
Endotoxin	< 1.0 EU/mg
Host Cell Protein	< 100 ppm
pH	6.0 ± 0.5 (for solution)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.