Description

(4-Boc-Aminophenyl)Boronic Acid is a high-purity, protected aniline boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation & Probe Synthesis: Used in the development of fluorescent probes, bioconjugates, and molecular imaging agents due to its reactive boronic acid group and protected amine.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and herbicides.
• Material Science: Serves as a monomer or linker in the creation of organic frameworks, polymers, and functionalized surfaces.
• Chemical Biology: Utilized for the site-specific modification of peptides, sugars, and other biomolecules.
• Process Chemistry & Scale-up: Provides a reliable, high-quality starting material for optimizing and scaling synthetic routes from lab to pilot plant.

Basic Information

Product Name	(4-Boc-Aminophenyl)Boronic Acid
CAS No.	380430-49-9
Molecular Formula	C11H16BNO4
Molecular Weight	237.06 g/mol
Synonyms	4-(Boc-amino)benzeneboronic acid; N-Boc-4-aminophenylboronic acid; tert-Butyl (4-boronophenyl)carbamate; 4-(tert-Butoxycarbonylamino)phenylboronic acid; 4-BocNH-PhB(OH)2; B-[4-[[(1,1-Dimethylethoxy)carbonyl]amino]phenyl]boronic acid; (4-((tert-Butoxycarbonyl)amino)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (4-Boc-Aminophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.