Description

D-Valine, n-Acetyl-3-Methyl-, Methyl Ester is a high-purity, non-natural amino acid derivative characterized by its specific D-configuration and acetylated, esterified structure. This compound is a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, stereochemically defined intermediates for drug discovery, process development, and the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for protease inhibitors and other targeted therapies.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to incorporate D-valine analogs into peptide chains.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway research, and investigations into amino acid metabolism and transport.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality in complex organic molecules.
• Fine Chemical Production: An intermediate in the custom synthesis of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	D-Valine, n-Acetyl-3-Methyl-, Methyl Ester
CAS No.	380380-11-0
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	Methyl N-acetyl-3-methyl-D-valinate; D-Valine, N-acetyl-3-methyl-, methyl ester; N-Acetyl-3-methyl-D-valine methyl ester; Methyl (2R)-2-acetamido-3-methylbutanoate; (R)-Methyl 2-acetamido-3-methylbutanoate; Ac-D-MeVal-OMe; N-Acetyl-D-3-methylvaline methyl ester
EINECS	Contact for details

Quality Control

Our D-Valine, n-Acetyl-3-Methyl-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (D-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.