Description

(+)-N,n-Bis[(1S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, (11Br) is a chiral phosphoramidite ligand, a sophisticated organophosphorus compound designed for asymmetric synthesis. This compound is highly valued for its role as a precise catalyst component in enantioselective transformations, enabling the production of single-isomer intermediates critical for advanced materials and pharmaceuticals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require high stereochemical control.

Application

• Asymmetric Catalysis: As a key ligand for transition metal complexes (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, hydroformylation, and C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: For the stereocontrolled manufacture of chiral active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Production: In the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Advanced Material Research: For developing chiral polymers, liquid crystals, and molecular recognition systems.
• Methodology Development: Used in academic and industrial R&D laboratories to explore new catalytic asymmetric processes.
• Fine Chemical Manufacturing: Enabling the commercial-scale production of high-value, single-enantiomer flavor and fragrance compounds.

Basic Information

Product Name	(+)-N,n-Bis[(1S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, (11Br)
CAS No.	380230-02-4
Molecular Formula	C38H31NO2P
Molecular Weight	564.63 g/mol
Synonyms	(11bR)-4-[Bis[(1S)-1-phenylethyl]amino]-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; (R)-(-)-2,2'-Bis[(S)-1-phenylethylamino]-1,1'-binaphthyl-2,2'-diyl phosphite; (R)-(-)-2,2'-Bis[(S)-1-phenylethylamino]-1,1'-binaphthyl-2,2'-diyl hydrogen phosphite; (R)-BINAPAM; Chiral Phosphoramidite Ligand (R,S)-PE-BINAPHOS variant; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Identity, chiral purity, and chemical purity are verified using advanced analytical techniques including HPLC, NMR, and chiral chromatography. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess (ee), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is moisture-sensitive and easily oxidized; prolonged exposure to air or humidity must be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.