Description

tert-Butyl (5-Chloro-1,3-Benzodioxol-4-Yl)Carbamate is a high-purity, protected amine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and antimicrobial research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Peptide Mimetics & PROTACs: Serves as a protected amine precursor in the design of peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs).
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: A building block for novel polymers and functional organic materials.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	tert-Butyl (5-Chloro-1,3-Benzodioxol-4-Yl)Carbamate
CAS No.	379229-84-2
Molecular Formula	C12H14ClNO4
Molecular Weight	271.70 g/mol
Synonyms	5-Chloro-1,3-benzodioxol-4-amine, N-Boc derivative; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-chloro-1,3-benzodioxole; 5-Chloro-4-((tert-butoxycarbonyl)amino)benzo[d][1,3]dioxole; Boc-5-Chloro-1,3-benzodioxol-4-amine; tert-Butyl N-(5-chloro-1,3-benzodioxol-4-yl)carbamate; N-Boc-5-chloro-1,3-benzodioxol-4-amine; 379229-84-2; Boc-5-chloro-benzo[1,3]dioxol-4-yl-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Chloro-1,3-Benzodioxol-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.