Description

3,4-Difluoro-Benzenepropanamine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which can dramatically influence the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and oncology research programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Polymer Modification: Incorporated as a functional monomer to create specialty polymers with unique surface properties and chemical resistance.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reactions involving fluorinated amines.
• Fluorinated Surfactant Precursor: Used in the synthesis of specialty surfactants for demanding industrial applications.

Basic Information

Product Name	3,4-Difluoro-Benzenepropanamine
CAS No.	377083-92-6
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	3-(3,4-Difluorophenyl)propan-1-amine; 3,4-Difluorophenethylamine; 3,4-Difluoro-β-phenylethylamine; 3,4-DFPEA; 1-Amino-3-(3,4-difluorophenyl)propane; Benzenepropanamine, 3,4-difluoro-; 3,4-Difluorobenzeneethanamine, homoveratrylamine analog
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-Benzenepropanamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high reliability, from early-stage R&D to scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.