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2-Propenoic Acid, 3-[2-(Trifluoromethyl)Phenyl]-, Ethyl Ester, (2E)- CAS NO 376641-48-4
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CAS No.:376641-48-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Propenoic Acid, 3-[2-(Trifluoromethyl)Phenyl]-, Ethyl Ester, (2E)- is a specialized fluorinated acrylate ester monomer of significant interest in advanced material synthesis. This compound matters for its unique structural features, combining an α,β-unsaturated ester with a trifluoromethylphenyl group, which imparts valuable properties like chemical resistance, thermal stability, and potential hydrophobicity to resulting polymers. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel high-performance materials, including coatings, adhesives, and functional intermediates.
Application
- Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
- Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group is a critical pharmacophore for biological activity.
- Specialty Polymer Monomer: A valuable comonomer for creating fluorinated acrylic polymers and copolymers with improved chemical, thermal, and surface properties for high-performance coatings and films.
- Material Science R&D: Employed in developing novel materials such as liquid crystal displays (LCDs), optical films, and low-surface-energy coatings.
- Organic Synthesis Building Block: Utilized in Michael addition reactions, cycloadditions, and other transformations to construct complex fluorinated organic molecules.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-Propenoic Acid, 3-[2-(Trifluoromethyl)Phenyl]-, Ethyl Ester, (2E)- |
| CAS No. | 376641-48-4 |
| Molecular Formula | C₁₂H₁₁F₃O₂ |
| Molecular Weight | 244.21 g/mol |
| Synonyms | (2E)-3-[2-(Trifluoromethyl)phenyl]prop-2-enoic acid ethyl ester; Ethyl (2E)-3-[2-(trifluoromethyl)phenyl]acrylate; Ethyl (E)-3-(2-(trifluoromethyl)phenyl)acrylate; 2-Propenoic acid, 3-[2-(trifluoromethyl)phenyl]-, ethyl ester, (E)-; (E)-Ethyl 3-(2-(trifluoromethyl)phenyl)acrylate; α,β-Unsaturated ester with trifluoromethylphenyl group; Fluorinated acrylate ester monomer |
| EINECS | Contact for details |
Quality Control
Our 2-Propenoic Acid, 3-[2-(Trifluoromethyl)Phenyl]-, Ethyl Ester, (2E)- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Isomeric Purity (E/Z ratio) | ≥ 98:2 (E:Z) |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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