Description

Ethyl 3-(2,5-Difluorophenyl)Acrylate is a high-purity fluorinated acrylate ester building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the (2,5-difluorophenyl)acryloyl moiety, a key structural feature in the development of active pharmaceutical ingredients and functional materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl group.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and resins with tailored optical or surface properties.
• Chemical Research: Employed in academic and industrial laboratories for method development, catalysis studies, and the creation of complex organic frameworks.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display and lighting materials.

Basic Information

Product Name	Ethyl 3-(2,5-Difluorophenyl)Acrylate
CAS No.	375368-91-5
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	Ethyl (2E)-3-(2,5-Difluorophenyl)prop-2-enoate; (E)-Ethyl 3-(2,5-difluorophenyl)acrylate; 2-Propenoic acid, 3-(2,5-difluorophenyl)-, ethyl ester; Ethyl (E)-3-(2,5-difluorophenyl)acrylate; trans-Ethyl 3-(2,5-difluorophenyl)acrylate; 375368-91-5; Acrylic acid, 3-(2,5-difluorophenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2,5-Difluorophenyl)Acrylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (GC/HPLC)	≥ 99.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.