Description

Ethyl 23Difluorocinnamate is a high-purity fluorinated cinnamate derivative, identified by CAS NO 375368-90-4. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for synthesizing complex organic molecules. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and fungicides with enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Fluorinated component used in the research and production of advanced electronic display materials.
• Organic Synthesis & Catalysis: Versatile reagent for cross-coupling reactions and the construction of complex fluorinated aromatic systems in academic and industrial research.
• Flavor & Fragrance Chemistry: Intermediate for creating specialized aromatic compounds with modified stability and scent profiles.
• Polymer Modification: Used to introduce fluorinated side chains into polymers to alter surface properties, such as hydrophobicity and chemical resistance.

Basic Information

Product Name	Ethyl 23Difluorocinnamate
CAS No.	375368-90-4
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	Ethyl 2,3-Difluorocinnamate; 2,3-Difluorocinnamic Acid Ethyl Ester; Ethyl (2,3-Difluorophenyl)acrylate; (E)-Ethyl 3-(2,3-difluorophenyl)acrylate; Ethyl (E)-3-(2,3-difluorophenyl)-2-propenoate; 375368-90-4; Propenoic acid, 3-(2,3-difluorophenyl)-, ethyl ester, (E)-
EINECS	Contact for details

Quality Control

Our Ethyl 23Difluorocinnamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request. We support custom synthesis and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.