Description

(Phe1,Ser2)-Thrombin Receptor Activator Peptide 6 is a synthetic peptide agonist specifically designed to activate protease-activated receptor 1 (PAR-1), a key thrombin receptor involved in platelet aggregation and cellular signaling. This high-purity peptide is critical for researchers and developers in the life sciences sector, providing a reliable tool for studying hemostasis, thrombosis, and related vascular biology pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on cardiovascular and coagulation research.

Application

• Biomedical Research: A key reagent for in vitro and in vivo studies of platelet activation, thrombosis models, and PAR-1 receptor signaling mechanisms.
• Drug Discovery & Development: Used as a reference standard and pharmacological tool in screening assays for novel antiplatelet and antithrombotic therapeutics.
• Cell Biology Studies: Employed to investigate the role of thrombin and PAR-1 in cellular processes such as proliferation, inflammation, and endothelial cell function.
• Diagnostic Assay Development: Serves as a critical component in the calibration and validation of diagnostic kits designed to measure platelet function or coagulation pathways.
• Signal Transduction Research: A precise agonist for dissecting G-protein coupled receptor (GPCR) pathways downstream of thrombin receptor activation.

Basic Information

Product Name	(Phe1,Ser2)-Thrombin Receptor Activator Peptide 6
CAS No.	374898-11-0
Molecular Formula	C41H56N10O10
Molecular Weight	848.96 g/mol
Synonyms	TRAP-6; Thrombin Receptor Activator Peptide-6; SFLLRN-NH2 (Ser-Phe-Leu-Leu-Arg-Asn-NH2); PAR-1 Agonist Peptide; Protease-Activated Receptor 1 Agonist; SFLLRN; (Ser-Phe-Leu-Leu-Arg-Asn) Amide; H-Ser-Phe-Leu-Leu-Arg-Asn-NH2
EINECS	Contact for details

Quality Control

Our (Phe1,Ser2)-Thrombin Receptor Activator Peptide 6 is manufactured under stringent conditions to ensure exceptional purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to rigorous quality testing protocols, and specifications can be tailored to meet specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.