Description

trans-3-Fluoro-4-Methylpiperidine Hydrochloride (Wx601381) is a high-purity, fluorinated piperidine derivative offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of central nervous system (CNS) active drugs and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for improved biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring new fluorinated heterocyclic compounds and their properties.
• Process Chemistry: Integrated into scalable synthetic routes for the manufacture of complex molecules requiring a fluorinated piperidine moiety.

Basic Information

Product Name	trans-3-Fluoro-4-Methylpiperidine Hydrochloride (Wx601381)
CAS No.	374794-76-0
Molecular Formula	C6H13ClFN
Molecular Weight	153.63 g/mol
Synonyms	trans-3-Fluoro-4-methylpiperidine HCl; (3R,4S)-3-Fluoro-4-methylpiperidine hydrochloride; (3S,4R)-3-Fluoro-4-methylpiperidine hydrochloride; 4-Methyl-3-fluoropiperidine hydrochloride; 3-Fluoro-4-methylpiperidine hydrochloride (trans); WX-601381; Wx601381
EINECS	Contact for details

Quality Control

Our trans-3-Fluoro-4-Methylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and consistent isomeric composition. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.