Description

Ba-D-Glucopyranuronic Acid, 1-Deoxy-1-Fluoro-5-C-Fluoro- (9Ci) is a specialized fluorinated carbohydrate derivative, a key building block in advanced synthetic chemistry. This compound is valued for its role as a stable glycosyl donor or a metabolic probe, enabling precise modifications to sugar-based molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel glycotherapeutics, enzyme inhibitors, and diagnostic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs and other bioactive molecules targeting viral and metabolic diseases.
• Glycobiology Research: Used as a stable, non-hydrolyzable analog of glucuronic acid to study enzyme mechanisms, carbohydrate-protein interactions, and metabolic pathways.
• Probe Development: Serves as a molecular probe in 19F NMR spectroscopy and positron emission tomography (PET) tracer development due to its fluorine atoms.
• Chemical Biology Tool: Employed to investigate glycosyltransferases and glycosidases, aiding in drug discovery for cancer and inflammation.
• Process Chemistry: Utilized in process development and scale-up for the manufacture of complex fluorinated active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Ba-D-Glucopyranuronic Acid, 1-Deoxy-1-Fluoro-5-C-Fluoro- (9Ci)
CAS No.	374105-93-8
Molecular Formula	C6H8F2O6
Molecular Weight	214.12 g/mol
Synonyms	1-Deoxy-1,5-difluoro-D-glucuronic acid; 1,5-Dideoxy-1,5-difluoro-D-glucuronic acid; 1,5-Difluoro-1,5-dideoxy-D-glucuronic acid; Ba-D-1,5-Difluoroglucuronic Acid; (2S,3S,4S,5R)-3,4,5-Trihydroxy-2,6-difluoro-6-oxohexanoic Acid; 1,5-Difluoro-1,5-dideoxy-D-glucopyranuronic Acid; Difluoroglucuronic Acid
EINECS	Contact for details

Quality Control

Every batch of Ba-D-Glucopyranuronic Acid, 1-Deoxy-1-Fluoro-5-C-Fluoro- (9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your research and development needs. A detailed Certificate of Analysis (COA) including HPLC purity, NMR confirmation, and residual solvent analysis is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.