Description

4-Penten-1-One, 2,2-Difluoro-4-Methyl-1-Phenyl- (9Ci) is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring a difluoro-substituted pentenone backbone attached to a phenyl ring, which enables precise control over reactivity and stereochemistry in complex molecule construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the difluoro and ketone functionalities contribute to biological activity and environmental persistence profiles.
• Material Science Research: Acts as a precursor for novel fluorinated polymers or specialty monomers, exploring properties like chemical resistance and low surface energy.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecular frameworks via reactions such as Michael additions, cyclizations, and cross-couplings.
• Ligand and Catalyst Development: Utilized in the design and synthesis of new chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	4-Penten-1-One, 2,2-Difluoro-4-Methyl-1-Phenyl- (9Ci)
CAS No.	373393-26-1
Molecular Formula	C12H12F2O
Molecular Weight	210.22 g/mol
Synonyms	2,2-Difluoro-4-methyl-1-phenyl-4-penten-1-one; 1-Phenyl-2,2-difluoro-4-methyl-4-penten-1-one; 4-Methyl-2,2-difluoro-1-phenyl-4-penten-1-one; 373393-26-1; 4-Penten-1-one, 2,2-difluoro-4-methyl-1-phenyl-; (9CI) Difluoromethylenated Pentenone Derivative
EINECS	Contact for details

Quality Control

Our 4-Penten-1-One, 2,2-Difluoro-4-Methyl-1-Phenyl- (9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.