Description

Sontuzumab CAS NO 372075-37-1 is a high-purity monoclonal antibody (mAb) for research and pharmaceutical development. This compound is critical for targeted cancer therapy research, specifically in the investigation of novel oncology treatments. It is essential for pharmaceutical manufacturers, biotech R&D laboratories, and academic institutions focused on immuno-oncology and biologics development.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of investigational and therapeutic monoclonal antibody drugs.
• Oncology Research: Key reagent in preclinical and clinical studies for evaluating targeted cancer therapies.
• Biologics Development: Used in process development, scale-up, and optimization for mAb production.
• Biochemical Assays: Serves as a standard or reference material in analytical method development and validation (e.g., ELISA, SPR).
• Cell Culture & Functional Studies: Applied in in vitro studies to assess mechanism of action, binding affinity, and cellular responses.
• Diagnostic Reagent Development: Potential use in the development of companion diagnostics for personalized medicine.

Basic Information

Product Name	Sontuzumab
CAS No.	372075-37-1
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Monoclonal Antibody)
Synonyms	Anti-EGFR Monoclonal Antibody
Sontuzumab (INN)
Monoclonal Antibody Sontuzumab
EGFR Inhibitor Sontuzumab
Investigational Anti-EGFR mAb
CAS 372075-37-1
Therapeutic Monoclonal Antibody
EINECS	Contact for details

Quality Control

Our Sontuzumab is manufactured under strict quality systems. Each batch is subjected to a comprehensive suite of analytical tests to ensure identity, purity, potency, and safety, adhering to relevant ICH guidelines. A detailed Certificate of Analysis (COA) documenting purity (by SEC-HPLC, CE-SDS), endotoxin levels, sterility, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at 2-8°C for short-term use or at -70°C or below for extended storage. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SEC-HPLC / CE-SDS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Concentration	As per COA
Endotoxin	< 1.0 EU/mg
Sterility	Sterile
Biological Activity (Cell-based Assay)	As per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.