Description

1-(Trifluoromethyl)Cyclopropanemethanol is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopropane ring and a trifluoromethyl group, makes it a critical intermediate for introducing conformational rigidity and lipophilicity into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials, improving their dielectric and optical properties.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex, fluorinated molecular architectures for various R&D applications.

Basic Information

Product Name	1-(Trifluoromethyl)Cyclopropanemethanol
CAS No.	371917-17-8
Molecular Formula	C5H7F3O
Molecular Weight	140.11 g/mol
Synonyms	(Trifluoromethyl)cyclopropylmethanol; Cyclopropanemethanol, 1-(trifluoromethyl)-; 1-(Trifluoromethyl)cyclopropylmethanol; α-(Trifluoromethyl)cyclopropanemethanol; (1-(Trifluoromethyl)cyclopropyl)methanol
EINECS	Contact for details

Quality Control

Our 1-(Trifluoromethyl)Cyclopropanemethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.