Description

2-Chloro-4-Iodobenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and pesticides with specific modes of action.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and materials science applications.
• Functional Material Development: Serves as a monomer or intermediate in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodo group.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	2-Chloro-4-Iodobenzonitrile
CAS No.	371764-70-4
Molecular Formula	C7H3ClIN
Molecular Weight	263.46 g/mol
Synonyms	4-Iodo-2-chlorobenzonitrile; 2-Chloro-4-iodobenzene carbonitrile; Benzonitrile, 2-chloro-4-iodo-; 2-Chloro-4-iodobenzonitrile; 2-Chloro-4-iodo-benzonitrile; 2-Chloro-4-iodobenzonitrile (CAS 371764-70-4); 2-Chloro-4-iodobenzonitrile, 97+%
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for prolonged storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.