Description

3-(3-Bromophenyl)-3-Oxo-2-(4-Oxo-3,4-Dihydro-2(1H)-Quinazolinylidene)Propanenitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinazolinone-based molecules with potential biological activity.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies in drug discovery programs.
• Kinase Inhibitor Development: Serves as a core structure in the research and development of potential kinase inhibitors for targeted cancer therapies.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Utilized in advanced organic synthesis for constructing complex nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	3-(3-Bromophenyl)-3-Oxo-2-(4-Oxo-3,4-Dihydro-2(1H)-Quinazolinylidene)Propanenitrile
CAS No.	371131-75-8
Molecular Formula	C₁₇H₁₀BrN₃O₂
Molecular Weight	368.19 g/mol
Synonyms	2-(3-Bromobenzoyl)-3-(4-oxo-3,4-dihydroquinazolin-2-yl)acrylonitrile; 3-(3-Bromophenyl)-3-oxo-2-(4-oxo-3,4-dihydroquinazolin-2-ylidene)propanenitrile; Propanenitrile, 3-(3-bromophenyl)-3-oxo-2-(4-oxo-3,4-dihydro-2(1H)-quinazolinylidene)-; (Z)-2-(3-Bromobenzoyl)-3-(4-oxo-3,4-dihydroquinazolin-2-yl)acrylonitrile; CAS 371131-75-8
EINECS	Contact for details

Quality Control

Our 3-(3-Bromophenyl)-3-Oxo-2-(4-Oxo-3,4-Dihydro-2(1H)-Quinazolinylidene)Propanenitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.