Description

Methyl 3,3,3-Trifluoro-2-(Tosylimino)Propionate is a high-value fluorinated building block and synthon used in advanced organic synthesis. This compound is critical for introducing the trifluoromethylimino moiety into target molecules, enabling the development of novel compounds with enhanced properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in protease inhibitors and kinase modulators.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science Precursor: Serves as a precursor for specialty polymers and advanced materials requiring fluorinated components for thermal or chemical resistance.
• Organic Synthesis Reagent: Acts as a versatile reagent for constructing complex heterocycles and introducing the CF3 group via imino-transfer reactions.
• Chemical Research: Employed in academic and industrial R&D for methodology development and exploring new reaction pathways in fluorine chemistry.

Basic Information

Product Name	Methyl 3,3,3-Trifluoro-2-(Tosylimino)Propionate
CAS No.	370877-57-9
Molecular Formula	C12H12F3NO4S
Molecular Weight	323.29 g/mol
Synonyms	Methyl 3,3,3-trifluoro-2-[(4-methylphenyl)sulfonyl]imino]propanoate; 2-[(Tosyl)imino]-3,3,3-trifluoropropionic Acid Methyl Ester; Methyl 2-[(4-Methylbenzenesulfonyl)imino]-3,3,3-trifluoropropanoate; Methyl α-(Tosylimino)-β,β,β-trifluoropropionate; Tosylimino-trifluoropropionate Methyl Ester; 370877-57-9; Methyl 3,3,3-trifluoro-2-(p-toluenesulfonylimino)propionate
EINECS	Contact for details

Quality Control

Our production of Methyl 3,3,3-Trifluoro-2-(Tosylimino)Propionate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the exacting requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.