Description

Cyclohexanecarbonitrile, 4-Ethynyl-4-Hydroxy-, trans- (9Ci) is a specialized, high-purity organic intermediate featuring a unique combination of a nitrile group, a hydroxyl group, and an ethynyl moiety on a cyclohexane ring. This compound matters as a versatile and valuable building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• As a key chiral intermediate in the synthesis of novel pharmaceutical candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Utilized in agrochemical research for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Serves as a precursor for advanced materials, such as liquid crystals and specialty polymers, where its rigid, functionalized structure is advantageous.
• Employed in academic and institutional research for methodological studies in asymmetric synthesis and catalysis.
• Used in the development of molecular probes and imaging agents for biochemical and diagnostic applications.

Basic Information

Product Name	Cyclohexanecarbonitrile, 4-Ethynyl-4-Hydroxy-, trans- (9Ci)
CAS No.	370147-92-5
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	trans-4-Ethynyl-4-hydroxycyclohexanecarbonitrile; 4-Ethynyl-4-hydroxycyclohexanecarbonitrile, trans-; (1r,4r)-4-Ethynyl-4-hydroxycyclohexanecarbonitrile; 4-Hydroxy-4-ethynylcyclohexanecarbonitrile; Cyclohexanecarbonitrile, 4-ethynyl-4-hydroxy-, (1r,4r)-; 370147-92-5; (trans)-4-Ethynyl-4-hydroxy-cyclohexanecarbonitrile
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonitrile, 4-Ethynyl-4-Hydroxy-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.