Description

Cyclohexanecarbonitrile, 4-Ethynyl-4-Hydroxy-, cis- (9Ci) is a specialized organic compound featuring a unique cis-configured cyclohexane ring substituted with a nitrile, a hydroxyl, and an ethynyl group. This molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of complex pharmaceutical intermediates and novel materials. It is primarily sought after by research institutions and fine chemical manufacturers engaged in medicinal chemistry, agrochemical research, and the synthesis of functionalized organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where its functional groups allow for the creation of novel bioactive molecules.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced organic electronic materials due to its ethynyl functionality.
• Academic & Industrial R&D: A critical reagent for method development and exploratory organic synthesis in university and corporate research laboratories.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Item	Detail
Product Name	Cyclohexanecarbonitrile, 4-Ethynyl-4-Hydroxy-, cis- (9Ci)
CAS No.	370147-90-3
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	cis-4-Ethynyl-4-hydroxycyclohexanecarbonitrile; (1r,4r)-4-Ethynyl-4-hydroxycyclohexane-1-carbonitrile; 4-Ethynyl-4-hydroxycyclohexanecarbonitrile (cis-); 4-Hydroxy-4-ethynylcyclohexanecarbonitrile; 1-Cyano-4-ethynyl-4-hydroxycyclohexane; cis-4-Hydroxy-4-ethynylcyclohexanecarbonitrile; 370147-90-3; 4-Ethynyl-4-hydroxycyclohexyl cyanide (cis-)
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonitrile, 4-Ethynyl-4-Hydroxy-, cis- (9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.