Description

Ethanone, 2,2,2-Trifluoro-1-[3-(Hydroxymethyl)Phenyl]- (9Ci) is a specialized fluorinated aromatic ketone building block, distinguished by its trifluoroacetyl and benzyl alcohol functional groups. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorine substitution pattern can significantly alter molecular properties. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those requiring trifluoromethyl ketone or fluorinated aromatic motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex organic molecules via reactions at the ketone or hydroxymethyl functional groups.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and material chemistry.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[3-(Hydroxymethyl)Phenyl]- (9Ci)
CAS No.	370104-02-2
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3-(Hydroxymethyl)phenyl Trifluoromethyl Ketone; 1-[3-(Hydroxymethyl)phenyl]-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-[3-(hydroxymethyl)phenyl]ethanone; α,α,α-Trifluoro-3-(hydroxymethyl)acetophenone; 3-(Trifluoroacetyl)benzyl Alcohol; (3-(Hydroxymethyl)phenyl)(trifluoromethyl)methanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-[3-(Hydroxymethyl)Phenyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.