Description

n-Hexanoyl Coenzyme A Lithium Salt (C6:0) is a high-purity, chemically defined acyl-CoA ester, a critical biochemical reagent for studying lipid metabolism and enzyme function. This compound serves as a vital substrate and intermediate in metabolic pathways, enabling precise research and development in life sciences. It is essential for biochemists, pharmaceutical researchers, and diagnostic manufacturers working on fatty acid oxidation, enzyme kinetics, and metabolic disorder studies.

Application

• Biochemical Research: Used as a defined substrate for studying acyl-CoA dehydrogenases, synthetases, and other enzymes involved in mitochondrial β-oxidation.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in drug discovery programs targeting metabolic diseases, such as disorders of fatty acid metabolism.
• Diagnostic Assays: Employed in the formulation of enzymatic test kits for clinical diagnostics to measure specific metabolic enzyme activities in tissue samples or bodily fluids.
• Metabolomics & Lipidomics: Acts as a critical analytical standard for the identification and quantification of acyl-CoA species in complex biological samples using LC-MS or HPLC techniques.
• Enzyme Characterization: Utilized in kinetic studies to determine Michaelis-Menten constants (Km and Vmax) and inhibitor potency for enzymes that process medium-chain acyl-CoAs.
• Cell Culture & Metabolism Studies: Applied in cell-based assays to investigate the effects of specific acyl-CoA pools on cellular signaling, gene expression, and metabolic flux.

Basic Information

Product Name	n-Hexanoyl Coenzyme A Lithium Salt (C6:0)
CAS No.	369656-99-5
Molecular Formula	C27H45N7O17P3S • xLi
Molecular Weight	Approx. 921.6 g/mol (Free acid)
Synonyms	Hexanoyl-CoA Lithium Salt; Caproyl-CoA Lithium Salt; Coenzyme A, S-hexanoate lithium salt; C6:0-CoA; Acyl-CoA (C6:0); Medium-chain acyl-CoA; S-Hexanoylcoenzyme A lithium salt; 3'-Phosphoadenosine 5'-(3-{(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-({2-[(1-oxohexyl)sulfanyl]ethyl})amino)propyl]amino}butyl) dihydrogen diphosphate) lithium salt
EINECS	Contact for details

Quality Control

Every batch of n-Hexanoyl Coenzyme A Lithium Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and stability. Our quality system is designed to meet the exacting requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by NMR/IR), and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR/IR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.