Description

Imidazol-1-Yl-Difluoromethyl-Diphenylphosphine is a specialized organophosphorus reagent featuring a reactive difluoromethylphosphine group. This compound is valued for its role as a versatile ligand and precursor in advanced synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for catalyst development and the synthesis of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for creating novel active pharmaceutical ingredients (APIs), particularly those incorporating fluorine atoms for enhanced metabolic stability and bioavailability.
• Catalyst Ligand Development: Serves as a precursor or ligand in transition metal catalysis for cross-coupling and other bond-forming reactions critical in fine chemical production.
• Agrochemical Research: Used in the research and development of new generation pesticides and herbicides where fluorinated motifs are desirable for activity.
• Material Science Precursor: Employed in the synthesis of specialized fluorinated polymers or ligands for advanced materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis within university and corporate research laboratories.

Basic Information

Product Name	Imidazol-1-Yl-Difluoromethyl-Diphenylphosphine
CAS No.	368873-85-2
Molecular Formula	C₁₆H₁₃F₂N₂P
Molecular Weight	302.26 g/mol
Synonyms	1-[(Difluoromethyl)diphenylphosphino]imidazole; Difluoromethyl(diphenyl)phosphine Imidazole Adduct; (Imidazol-1-yl)difluoromethyl-diphenylphosphorane; Imidazole-Difluoromethyl-Diphenylphosphine Adduct; Phosphine, [(1H-imidazol-1-yl)difluoromethyl]diphenyl-; 368873-85-2; 1-[(Difluoromethyl)(diphenyl)phosphanyl]-1H-imidazole
EINECS	Contact for details

Quality Control

Our Imidazol-1-Yl-Difluoromethyl-Diphenylphosphine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This material is easily oxidized and light-sensitive. Keep container tightly sealed in a dry and well-ventilated place. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.