Description

(S)-Pyrrolidine-2-Carboxylic Acid (4-Methoxy-Phenyl)-Amide is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized pyrrolidine core, which is a privileged scaffold in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Protease Inhibitor Scaffold: Serves as a core structural element in the design and synthesis of inhibitors for various proteolytic enzymes.
• Agrochemical Research: Used as a sophisticated intermediate in the synthesis of novel, high-efficacy pesticides and herbicides with specific chiral activity.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands or organocatalysts for stereoselective synthesis.
• Chemical Biology Probe: Employed in academic and industrial research to study biological pathways and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	(S)-Pyrrolidine-2-Carboxylic Acid (4-Methoxy-Phenyl)-Amide
CAS No.	367521-36-6
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	(S)-2-(4-Methoxybenzamido)pyrrolidine-1-carboxylic acid; L-Proline, 1-[(4-methoxyphenyl)carbonyl]-; (S)-1-(4-Methoxybenzoyl)pyrrolidine-2-carboxylic acid; (S)-N-(4-Methoxyphenyl)pyrrolidine-2-carboxamide; 4-Methoxy-N-[(2S)-pyrrolidin-2-yl]benzamide; (S)-Pyrrolidine-2-carboxylic acid (4-methoxyphenyl)amide; (2S)-N-(4-Methoxyphenyl)pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our (S)-Pyrrolidine-2-Carboxylic Acid (4-Methoxy-Phenyl)-Amide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.